Basic Information
ID: ALA4833732
Type: Functional
Description: Antitumor activity against human KARPAS-422 cells harboring EZH2 Y641N mutant xenografted in NCG mouse assessed as change in tumor weight at 200 mg/kg, po BID via gavage measured after 28 days (Rvb = 2.14 g)
Organism: Homo sapiens
Cell type: KARPAS-422
Activity Charts
Bioactivity
Activity Types for Assay ALA4833732
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 572.75 | 4.73 | 4.73 |
| 610.80 | 4.90 | 4.90 |