Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM measured upto 120 mins in presence of NADPH regenerating system ...

Basic Information

ID: ALA4833913

Type: ADME

Description: Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM measured upto 120 mins in presence of NADPH regenerating system by LC-MS/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  ADMET(ALA612558)

Document:  ALA4831547

Metabolic stability in human liver microsomes assessed as intrinsic clearance at 1 uM measured upto 120 mins in presence of NADPH regenerating system by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
407.585.685.68
339.05
321.11
353.11
334.14
421.57
334.14
348.17
322.09
364.17
395.15
320.12
334.14
393.05
388.11
334.14
407.08
349.16
365.16
334.14
335.13
334.14
365.12
379.03
311.15
363.18
334.14
350.21
335.13
353.11