Basic Information
ID: ALA4834037
Type: ADME
Description: Intrinsic clearance in human liver microsomes at 1 uM preincubated with NADPH for 5 mins followed by compound addition and measured upto 30 mins by LC-MS/MS analysis
Format: BAO_0000251
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Target: ADMET(ALA612558)
Document: ALA4831554
Intrinsic clearance in human liver microsomes at 1 uM preincubated with NADPH for 5 mins followed by compound addition and measured upto 30 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4834037
CL
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.40 | 3.18 | 3.18 |
| 431.43 | 2.47 | 2.47 |
| 430.44 | 2.90 | 2.90 |
| 432.42 | 3.33 | 3.33 |
| 416.42 | 2.97 | 2.97 |
| 394.41 | 2.31 | 2.31 |
| 460.47 | 2.73 | 2.73 |
| 461.50 | 3.12 | 3.12 |
| 392.39 | 2.50 | 2.50 |
| 474.50 | 3.08 | 3.08 |
| 449.45 | 1.76 | 1.76 |
| 395.39 | 2.13 | 2.13 |
| 368.37 | 1.94 | 1.94 |
| 463.47 | 2.11 | 2.11 |
| 391.41 | 2.97 | 2.97 |
| 394.41 | 2.31 | 2.31 |
| 406.42 | 2.71 | 2.71 |
| 392.39 | 2.40 | 2.40 |
| 434.43 | 3.07 | 3.07 |
| 390.42 | 3.58 | 3.58 |
| 404.40 | 3.06 | 3.06 |
| 394.41 | 2.33 | 2.33 |
| 500.53 | 3.23 | 3.23 |
| 376.39 | 3.55 | 3.55 |
| 406.42 | 2.71 | 2.71 |
| 377.38 | 3.60 | 3.60 |
| 394.41 | 2.31 | 2.31 |
| 382.40 | 2.18 | 2.18 |
| 381.37 | 2.57 | 2.57 |
| 403.42 | 3.37 | 3.37 |
| 392.39 | 2.40 | 2.40 |
| 460.51 | 3.44 | 3.44 |
| 392.39 | 2.47 | 2.47 |
| 391.41 | 2.97 | 2.97 |
| 449.45 | 1.76 | 1.76 |
| 417.40 | 2.37 | 2.37 |
| 473.51 | 3.03 | 3.03 |
| 404.40 | 3.06 | 3.06 |
| 406.42 | 2.71 | 2.71 |
| 392.39 | 2.47 | 2.47 |
| 433.44 | 2.87 | 2.87 |
| 529.58 | 3.45 | 3.45 |
| 421.44 | 2.51 | 2.51 |
| 437.48 | 2.73 | 2.73 |
| 382.40 | 2.18 | 2.18 |
| 396.43 | 2.57 | 2.57 |
| 405.39 | 2.46 | 2.46 |
| 403.42 | 3.37 | 3.37 |
| 386.39 | 1.79 | 1.79 |
| 418.43 | 3.09 | 3.09 |