Assay Report Card

Basic Information

ID: ALA4834162

Type: Binding

Description: Reversible inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current at 300 nM preincubated with compound followed by washout for 4 hrs by manual patch clamp based electrophysiological method relative to control

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
421.404.554.55