Assay Report Card

Basic Information

ID: ALA4834376

Type: Functional

Description: Antiplasmodial activity against luciferase expressing Plasmodium berghei sporozoites infected in HepG2 cells assessed as decrease in parasite infection at 2 uM incubated for 16 hrs followed by replacement with compound free medium and measured after 48 hrs post infection by IVIS spectrum in vivo imaging analysis relative to control

Organism: Plasmodium berghei

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
335.434.694.69
538.085.085.08
522.014.614.61
431.533.423.42
492.014.644.64