Assay Report Card

Basic Information

ID: ALA4834377

Type: Functional

Description: Antiplasmodial activity against luciferase expressing Plasmodium berghei sporozoites infected in HepG2 cells assessed as decrease in parasite infection at 10 uM incubated for 16 hrs followed by replacement with compound free medium measured after 48 hrs post infection by IVIS spectrum in vivo imaging analysis relative to control

Organism: Plasmodium berghei

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
335.434.694.69
538.085.085.08
522.014.614.61
431.533.423.42
492.014.644.64