Basic Information
ID: ALA4834499
Type: Binding
Description: Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: MDCK
Target: Urea transporter 2(ALA3739246)
Document: ALA4834390
Inhibition of rat UT-A1 expressed in MDCK cells incubated for 15 mins by fluorescence plate reader assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4834499
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 315.33 | 4.14 | 4.14 |
| 313.76 | 2.86 | 2.86 |
| 509.98 | 5.10 | 5.10 |
| 501.61 | 5.83 | 5.83 |
| 503.58 | 5.14 | 5.14 |
| 461.50 | 4.19 | 4.19 |
| 503.58 | 5.31 | 5.31 |
| 481.92 | 4.53 | 4.53 |
| 451.90 | 4.52 | 4.52 |
| 505.56 | 4.59 | 4.59 |
| 481.92 | 4.53 | 4.53 |
| 489.56 | 4.75 | 4.75 |
| 495.95 | 4.84 | 4.84 |
| 524.00 | 5.49 | 5.49 |
| 480.94 | 4.48 | 4.48 |
| 475.53 | 4.50 | 4.50 |
| 538.03 | 5.88 | 5.88 |
| 481.92 | 4.53 | 4.53 |
| 525.97 | 4.93 | 4.93 |
| 459.53 | 4.80 | 4.80 |
| 501.45 | 4.77 | 4.77 |
| 552.06 | 6.27 | 6.27 |
| 353.45 | 3.22 | 3.22 |
| 480.94 | 4.48 | 4.48 |
| 517.90 | 4.81 | 4.81 |
| 517.61 | 5.53 | 5.53 |
| 552.06 | 6.10 | 6.10 |
| 363.45 | 3.83 | 3.83 |
| 487.59 | 5.61 | 5.61 |
| 445.50 | 4.49 | 4.49 |
| 509.98 | 5.15 | 5.15 |
| 497.48 | 4.47 | 4.47 |
| 524.00 | 5.66 | 5.66 |
| 550.81 | 5.84 | 5.84 |
| 538.03 | 5.71 | 5.71 |
| 480.94 | 4.48 | 4.48 |
| 451.90 | 4.52 | 4.52 |
| 400.93 | 4.48 | 4.48 |
| 487.59 | 5.44 | 5.44 |
| 396.49 | 2.34 | 2.34 |
| 431.48 | 4.18 | 4.18 |
| 473.56 | 5.05 | 5.05 |
| 559.98 | 5.76 | 5.76 |
| 481.92 | 4.53 | 4.53 |
| 408.43 | 3.85 | 3.85 |