Metabolic stability in Sprague-Dawley rat liver microsomes assessed as compound remaining at 5 uM preincubated for 5 mins followed by NADPH addition a...

Basic Information

ID: ALA4834505

Type: ADME

Description: Metabolic stability in Sprague-Dawley rat liver microsomes assessed as compound remaining at 5 uM preincubated for 5 mins followed by NADPH addition and measured at 15 mins by LC/MS analysis

Format: BAO_0000251

Organism: Rattus norvegicus

Tissue: Liver

Subcellular Fraction: Microsome

Target:  ADMET(ALA612558)

Document:  ALA4834390

Metabolic stability in Sprague-Dawley rat liver microsomes assessed as compound remaining at 5 uM preincubated for 5 mins followed by NADPH addition and measured at 15 mins by LC/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
524.005.495.49
552.066.106.10