Basic Information
ID: ALA4834540
Type: Binding
Description: Displacement of BODIPY FL vindoline from GST-tagged human PXR LBD at 10 uM incubated for 60 mins by TR-FRET assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4834540
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 481.34 | 4.76 | 4.76 |
| 410.50 | 3.59 | 3.59 |
| 415.52 | 3.21 | 3.21 |
| 457.60 | 4.85 | 4.85 |
| 428.51 | 2.81 | 2.81 |
| 432.97 | 5.19 | 5.19 |
| 373.43 | 2.73 | 2.73 |
| 428.55 | 4.54 | 4.54 |
| 478.41 | 4.79 | 4.79 |
| 429.54 | 4.03 | 4.03 |
| 426.50 | 3.29 | 3.29 |
| 453.49 | 4.73 | 4.73 |
| 412.56 | 4.84 | 4.84 |
| 405.91 | 4.06 | 4.06 |
| 447.99 | 4.93 | 4.93 |
| 416.50 | 3.00 | 3.00 |
| 404.92 | 4.87 | 4.87 |
| 441.60 | 5.15 | 5.15 |
| 400.50 | 4.22 | 4.22 |
| 373.43 | 2.57 | 2.57 |
| 424.53 | 3.89 | 3.89 |
| 473.60 | 4.48 | 4.48 |
| 417.44 | 2.21 | 2.21 |
| 477.97 | 4.15 | 4.15 |
| 401.49 | 3.41 | 3.41 |
| 457.55 | 3.93 | 3.93 |
| 410.50 | 3.59 | 3.59 |
| 494.41 | 4.49 | 4.49 |
| 464.39 | 4.48 | 4.48 |
| 429.54 | 3.77 | 3.77 |
| 457.55 | 3.81 | 3.81 |
| 375.41 | 2.13 | 2.13 |
| 385.49 | 3.71 | 3.71 |
| 393.85 | 3.08 | 3.08 |
| 431.51 | 3.31 | 3.31 |
| 441.55 | 4.23 | 4.23 |
| 427.57 | 4.59 | 4.59 |
| 414.53 | 4.53 | 4.53 |
| 449.96 | 4.38 | 4.38 |
| 441.60 | 5.01 | 5.01 |
| 359.41 | 2.43 | 2.43 |
| 415.52 | 3.72 | 3.72 |
| 417.49 | 2.65 | 2.65 |
| 429.54 | 3.77 | 3.77 |
| 462.02 | 5.49 | 5.49 |
| 418.95 | 5.18 | 5.18 |
| 433.96 | 4.68 | 4.68 |
| 398.53 | 4.83 | 4.83 |
| 473.55 | 3.51 | 3.51 |
| 417.51 | 4.16 | 4.16 |
| 403.48 | 3.85 | 3.85 |
| 433.51 | 3.86 | 3.86 |
| 498.83 | 5.13 | 5.13 |
| 449.96 | 4.38 | 4.38 |
| 433.96 | 4.68 | 4.68 |
| 374.42 | 2.01 | 2.01 |
| 447.94 | 4.26 | 4.26 |
| 420.92 | 3.64 | 3.64 |
| 385.49 | 3.71 | 3.71 |
| 427.53 | 3.92 | 3.92 |
| 444.94 | 4.24 | 4.24 |
| 445.54 | 3.73 | 3.73 |
| 384.50 | 4.52 | 4.52 |
| 400.50 | 3.30 | 3.30 |
| 399.52 | 4.02 | 4.02 |
| 398.53 | 4.53 | 4.53 |
| 454.38 | 5.02 | 5.02 |
| 443.57 | 4.29 | 4.29 |
| 429.54 | 4.03 | 4.03 |
| 443.53 | 3.62 | 3.62 |
| 418.95 | 4.88 | 4.88 |
| 389.43 | 2.43 | 2.43 |
| 430.92 | 3.93 | 3.93 |
| 413.54 | 4.33 | 4.33 |
| 419.93 | 4.37 | 4.37 |
| 414.53 | 4.23 | 4.23 |
| 440.53 | 3.59 | 3.59 |