Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentrati...

Basic Information

ID: ALA4834652

Type: Binding

Description: Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentration 9 nM using Arg-AMC as substrate preincubated for 15 mins followed by substrate addition and measured every 10 mins for 300 mins by fluorescence based assay

Format: BAO_0000219

Organism: Homo sapiens

Target:  Leukotriene A4 hydrolase(ALA4618)

Document:  ALA4834397

Inhibition of recombinant full length N-terminal His6-tagged LTA4H (unknown origin) expressed in Escherichia coli BL21 DE3 cells at enzyme concentration 9 nM using Arg-AMC as substrate preincubated for 15 mins followed by substrate addition and measured every 10 mins for 300 mins by fluorescence based assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
396.432.542.54
406.402.592.59
333.391.711.71
357.802.922.92
200.242.972.97
295.352.402.40
392.782.122.12
373.802.462.46
329.793.133.13
396.432.542.54
373.802.592.59
373.802.592.59
329.793.313.31
367.411.761.76
367.411.861.86
329.793.133.13
381.442.152.15
358.793.653.65
374.791.981.98
392.782.122.12
371.360.730.73
367.411.861.86
219.250.310.31
359.772.202.20
344.763.263.26
357.352.072.07
315.762.742.74