Basic Information
ID: ALA4834661
Type: Binding
Description: Inhibition of LTA4H in human whole blood assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation preincubated for 15 mins followed by ionophore stimulation and measured after 15 hrs by EIA assay
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4834661
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.43 | 2.54 | 2.54 |
| 406.40 | 2.59 | 2.59 |
| 333.39 | 1.71 | 1.71 |
| 357.80 | 2.92 | 2.92 |
| 295.35 | 2.40 | 2.40 |
| 392.78 | 2.12 | 2.12 |
| 373.80 | 2.46 | 2.46 |
| 329.79 | 3.13 | 3.13 |
| 396.43 | 2.54 | 2.54 |
| 373.80 | 2.59 | 2.59 |
| 373.80 | 2.59 | 2.59 |
| 329.79 | 3.31 | 3.31 |
| 367.41 | 1.76 | 1.76 |
| 367.41 | 1.86 | 1.86 |
| 329.79 | 3.13 | 3.13 |
| 381.44 | 2.15 | 2.15 |
| 358.79 | 3.65 | 3.65 |
| 374.79 | 1.98 | 1.98 |
| 392.78 | 2.12 | 2.12 |
| 371.36 | 0.73 | 0.73 |
| 367.41 | 1.86 | 1.86 |
| 359.77 | 2.20 | 2.20 |
| 344.76 | 3.26 | 3.26 |
| 357.35 | 2.07 | 2.07 |
| 315.76 | 2.74 | 2.74 |