Basic Information
ID: ALA4834663
Type: Binding
Description: Displacement of [3H]dofetilide from recombinant human ERG stably expressed in HEK293 cell membranes measured after 90 mins by microbeta liquid scintillation counting method
Format: BAO_0000249
Organism: Homo sapiens
Cell type: HEK293
Subcellular Fraction: Cell membrane
Target: HERG(ALA240)
Document: ALA4834397
Displacement of [3H]dofetilide from recombinant human ERG stably expressed in HEK293 cell membranes measured after 90 mins by microbeta liquid scintillation counting method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4834663
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.80 | 2.92 | 2.92 |
| 295.35 | 2.40 | 2.40 |
| 392.78 | 2.12 | 2.12 |
| 373.80 | 2.46 | 2.46 |
| 329.79 | 3.13 | 3.13 |
| 373.80 | 2.59 | 2.59 |
| 373.80 | 2.59 | 2.59 |
| 329.79 | 3.31 | 3.31 |
| 329.79 | 3.13 | 3.13 |
| 358.79 | 3.65 | 3.65 |
| 359.77 | 2.20 | 2.20 |
| 344.76 | 3.26 | 3.26 |
| 315.76 | 2.74 | 2.74 |