Basic Information
ID: ALA4834669
Type: Functional
Description: Ex-vivo inhibition of LTA4H in blood isolated from C57/BL6 mouse assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation at 10 mg/kg, po measured after 14 hrs by EIA assay
Organism: Mus musculus
Strain: C57/BL6
Activity Charts
Bioactivity
Activity Types for Assay ALA4834669
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.43 | 2.54 | 2.54 |
| 406.40 | 2.59 | 2.59 |
| 333.39 | 1.71 | 1.71 |
| 392.78 | 2.12 | 2.12 |
| 396.43 | 2.54 | 2.54 |
| 373.80 | 2.59 | 2.59 |
| 373.80 | 2.59 | 2.59 |
| 367.41 | 1.76 | 1.76 |
| 367.41 | 1.86 | 1.86 |
| 381.44 | 2.15 | 2.15 |
| 374.79 | 1.98 | 1.98 |
| 392.78 | 2.12 | 2.12 |
| 371.36 | 0.73 | 0.73 |
| 367.41 | 1.86 | 1.86 |
| 357.35 | 2.07 | 2.07 |