Basic Information
ID: ALA4834729
Type: Functional
Description: Ex-vivo inhibition of LTA4H in blood isolated from C57/BL6 mouse assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation at 0.625 mg/kg, po BID for 3 days measured after 2 hrs post last dose by EIA assay relative to control
Organism: Mus musculus
Strain: C57/BL6
Activity Charts
Bioactivity
Activity Types for Assay ALA4834729
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.78 | 2.12 | 2.12 |