Basic Information
ID: ALA4834729
Type: Functional
Description: Ex-vivo inhibition of LTA4H in blood isolated from C57/BL6 mouse assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation at 0.625 mg/kg, po BID for 3 days measured after 2 hrs post last dose by EIA assay relative to control
Format: BAO_0000218
Organism: Mus musculus
Strain: C57/BL6
Target: Leukotriene A4 hydrolase(ALA3738)
Document: ALA4834397
Ex-vivo inhibition of LTA4H in blood isolated from C57/BL6 mouse assessed as reduction of calcium ionophore A23187-stimulated LTB4 generation at 0.625 mg/kg, po BID for 3 days measured after 2 hrs post last dose by EIA assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4834729
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.78 | 2.12 | 2.12 |