Assay Report Card

Basic Information

ID: ALA4834926

Type: Functional

Description: Antiobesity activity in high fat diet-induced obese Sprague-Dawley rat model assessed as effect on plasma glucose level at 10 to 30 mg/kg, po QD administered for 10 weeks under HFD condition followed by overnight fasting prior to compound redosing on day 58/59 and subsequent glucose challenge 60 mins post compound last dose and measured at baseline 1 by OGTT

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
325.802.622.62
297.741.841.84
275.311.121.12