Basic Information
ID: ALA4834927
Type: Functional
Description: Antidiabetic activity in high fat diet-induced obese Sprague-Dawley rat model assessed as effect on plasma insulin level at 10 to 30 mg/kg, po administered for 10 weeks under HFD condition followed by overnight fasting prior to compound redosing on day 58/59 and subsequent glucose challenge 60 mins post compound last dose and measured at baseline 1 by OGTT
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA4834927
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 325.80 | 2.62 | 2.62 |
| 297.74 | 1.84 | 1.84 |
| 275.31 | 1.12 | 1.12 |