Basic Information
ID: ALA4834975
Type: Functional
Description: Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as desensitization of zaprinast-induced DMR response preincubated for 1 hr followed by zaprinast stimulation by DMR desensitization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HT-29
Target: G-protein coupled receptor 35(ALA1293267)
Document: ALA4834401
Agonist activity at human GPR35 receptor expressed in HT-29 cells assessed as desensitization of zaprinast-induced DMR response preincubated for 1 hr followed by zaprinast stimulation by DMR desensitization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4834975
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.21 | 0.55 | 0.55 |
| 314.25 | 1.07 | 1.07 |
| 285.05 | 1.96 | 1.96 |
| 408.32 | 2.97 | 2.97 |
| 288.28 | 2.93 | 2.93 |
| 420.37 | 4.09 | 4.09 |
| 381.09 | 2.06 | 2.06 |
| 381.09 | 2.06 | 2.06 |
| 342.31 | 2.51 | 2.51 |
| 324.33 | 3.99 | 3.99 |
| 312.28 | 2.87 | 2.87 |
| 405.12 | 1.54 | 1.54 |
| 378.29 | 2.96 | 2.96 |
| 408.32 | 2.97 | 2.97 |
| 312.28 | 2.87 | 2.87 |
| 352.25 | 2.45 | 2.45 |
| 300.24 | 3.00 | 3.00 |
| 408.32 | 2.97 | 2.97 |
| 307.23 | 0.95 | 0.95 |
| 396.28 | 3.10 | 3.10 |
| 316.22 | 1.60 | 1.60 |
| 384.32 | 3.02 | 3.02 |
| 284.34 | 3.57 | 3.57 |
| 396.28 | 3.10 | 3.10 |
| 408.32 | 2.97 | 2.97 |
| 318.19 | 1.00 | 1.00 |
| 408.32 | 2.97 | 2.97 |
| 300.24 | 3.00 | 3.00 |
| 426.31 | 3.11 | 3.11 |
| 282.25 | 2.86 | 2.86 |
| 300.24 | 3.00 | 3.00 |
| 351.15 | 3.79 | 3.79 |
| 312.28 | 2.87 | 2.87 |
| 408.32 | 2.97 | 2.97 |
| 302.19 | 1.30 | 1.30 |