Basic Information
ID: ALA4835003
Type: Binding
Description: Inhibition of SAE in human HCT116 cells assessed as redistribution of SUMO2/3 proteins from nucleus to cytosol preincubated for 2 hrs followed by compound washout and measured immediately by immunofluorescence assay
Organism: Homo sapiens
Cell type: HCT-116
Activity Charts
Bioactivity
Activity Types for Assay ALA4835003
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 530.63 | 2.20 | 2.20 |
| 544.66 | 2.51 | 2.51 |
| 553.06 | 2.58 | 2.58 |
| 599.52 | 3.51 | 3.51 |
| 553.06 | 2.45 | 2.45 |
| 573.48 | 2.93 | 2.93 |
| 523.04 | 2.78 | 2.78 |
| 552.08 | 2.55 | 2.55 |
| 567.49 | 2.89 | 2.89 |
| 564.09 | 2.43 | 2.43 |
| 580.09 | 2.56 | 2.56 |
| 539.04 | 2.28 | 2.28 |
| 552.08 | 2.42 | 2.42 |
| 537.06 | 3.09 | 3.09 |
| 565.07 | 2.86 | 2.86 |
| 538.05 | 2.24 | 2.24 |
| 578.12 | 2.74 | 2.74 |
| 574.47 | 2.32 | 2.32 |
| 529.64 | 1.78 | 1.78 |
| 551.42 | 1.49 | 1.49 |
| 557.48 | 3.44 | 3.44 |
| 545.64 | 1.91 | 1.91 |
| 598.53 | 3.08 | 3.08 |
| 572.50 | 2.90 | 2.90 |
| 614.50 | 0.92 | 0.92 |