Assay Report Card

Basic Information

ID: ALA4835005

Type: Binding

Description: Inhibition of SAE in human HCT116 cells xenografted in NCr nude mouse assessed as reduction in SUMO2/3 protein conjugates at 50 mg/kg, iv and measured up to 16 hrs by immunohistochemistry analysis

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
579.103.163.16
578.122.742.74