Assay Report Card

Basic Information

ID: ALA4835007

Type: Binding

Description: Inhibition of SAE in human HCT116 cells xenografted in NCr nude mouse assessed as improvement in SUMO-inhibitor adduct durability at 50 mg/kg, iv and measured up to 16 hrs by mass spectrometry

Organism: Homo sapiens

Cell type: HCT-116

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
579.103.163.16
578.122.742.74