Basic Information
ID: ALA4835058
Type: Binding
Description: Inhibition of full length human C-terminal His-tagged HDAC3/human N-terminal GST-agged NCOR2 using fluorogenic acetylated peptide as substrate incubated for 30 mins by fluorescence plate reader assay
Format: BAO_0000223
Organism: Homo sapiens
Target: Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(ALA2111363)
Document: ALA4834403
Inhibition of full length human C-terminal His-tagged HDAC3/human N-terminal GST-agged NCOR2 using fluorogenic acetylated peptide as substrate incubated for 30 mins by fluorescence plate reader assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4835058
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 264.32 | 2.47 | 2.47 |
| 478.64 | 5.18 | 5.18 |
| 492.66 | 5.43 | 5.43 |
| 612.77 | 7.18 | 7.18 |
| 612.77 | 7.07 | 7.07 |
| 536.67 | 5.40 | 5.40 |
| 615.74 | 4.91 | 4.91 |
| 613.76 | 5.87 | 5.87 |
| 517.59 | 4.66 | 4.66 |
| 519.56 | 3.45 | 3.45 |
| 425.49 | 4.30 | 4.30 |
| 599.73 | 5.88 | 5.88 |
| 434.45 | 3.95 | 3.95 |
| 518.57 | 4.06 | 4.06 |
| 627.79 | 6.12 | 6.12 |
| 612.77 | 7.07 | 7.07 |
| 425.49 | 4.30 | 4.30 |
| 504.55 | 3.81 | 3.81 |
| 439.51 | 4.54 | 4.54 |
| 535.65 | 3.41 | 3.41 |
| 433.46 | 4.55 | 4.55 |
| 549.68 | 3.65 | 3.65 |
| 606.72 | 7.07 | 7.07 |
| 536.65 | 5.33 | 5.33 |
| 530.63 | 5.26 | 5.26 |
| 530.63 | 5.41 | 5.41 |
| 619.81 | 5.86 | 5.86 |
| 613.76 | 6.12 | 6.12 |
| 494.59 | 4.23 | 4.23 |
| 544.61 | 4.30 | 4.30 |
| 601.71 | 4.43 | 4.43 |