Basic Information
ID: ALA4835126
Type: Binding
Description: Displacement of fluorescent tracer 5-(3-(4-((1S,5S,6S)-10-(3,5-dichlorophenylsulfonyl)-2-oxo-3-(pyridin-3-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl)-1H-1,2,3-triazol-1-yl)propylcarbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate from recombinant full length C-terminal FLAG-tagged FKBP12 (unknown origin) expressed in Escherichia coli BL21 (DE2) cells incubated for 30 mins by fluorescence polarisation competition binding assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4835126
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 715.88 | 7.84 | 7.84 |
| 741.92 | 8.40 | 8.40 |
| 787.99 | 8.64 | 8.64 |
| 787.99 | 8.64 | 8.64 |
| 785.98 | 8.42 | 8.42 |
| 771.95 | 8.03 | 8.03 |
| 701.86 | 7.45 | 7.45 |
| 761.91 | 6.18 | 6.18 |
| 757.92 | 7.80 | 7.80 |
| 701.86 | 7.45 | 7.45 |
| 771.95 | 8.03 | 8.03 |
| 773.96 | 8.25 | 8.25 |
| 771.95 | 8.03 | 8.03 |
| 743.94 | 8.62 | 8.62 |
| 729.91 | 8.23 | 8.23 |
| 741.92 | 8.40 | 8.40 |
| 743.89 | 7.41 | 7.41 |
| 741.92 | 8.40 | 8.40 |
| 771.95 | 8.03 | 8.03 |
| 787.95 | 7.43 | 7.43 |
| 741.92 | 8.40 | 8.40 |
| 727.90 | 8.01 | 8.01 |
| 743.94 | 8.62 | 8.62 |
| 761.91 | 6.18 | 6.18 |
| 727.90 | 8.01 | 8.01 |
| 729.91 | 8.23 | 8.23 |
| 773.96 | 8.25 | 8.25 |
| 727.90 | 8.01 | 8.01 |
| 757.92 | 7.80 | 7.80 |
| 703.87 | 7.70 | 7.70 |
| 785.98 | 8.42 | 8.42 |
| 761.91 | 6.18 | 6.18 |
| 743.89 | 7.41 | 7.41 |
| 715.88 | 7.84 | 7.84 |