Assay Report Card

Basic Information

ID: ALA4835127

Type: Binding

Description: Selectivity ratio of Kd for displacement of fluorescent tracer 5-(3-(4-((1S,5S,6S)-10-(3,5-dichlorophenylsulfonyl)-2-oxo-3-(pyridin-3-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl)-1H-1,2,3-triazol-1-yl)propylcarbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate from recombinant full length C-terminal FLAG-tagged FJBP12 to Kd for displacement of fluorescent tracer 5-(3-(4-((1S,5S,6S)-10-(3,5-dichlorophenylsulfonyl)-2-oxo-3-(pyridin-3-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl)-1H-1,2,3-triazol-1-yl)propylcarbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate from recombinant full length C-terminal FLAG-tagged FKBP51 (unknown origin)

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
715.887.847.84
741.928.408.40
787.998.648.64
787.998.648.64
785.988.428.42
771.958.038.03
701.867.457.45
761.916.186.18
757.927.807.80
701.867.457.45
771.958.038.03
773.968.258.25
771.958.038.03
743.948.628.62
729.918.238.23
741.928.408.40
743.897.417.41
741.928.408.40
771.958.038.03
787.957.437.43
741.928.408.40
727.908.018.01
743.948.628.62
761.916.186.18
727.908.018.01
729.918.238.23
773.968.258.25
727.908.018.01
757.927.807.80
703.877.707.70
785.988.428.42
761.916.186.18
743.897.417.41
715.887.847.84