Displacement of fluorescent tracer 5-(3-(4-((1S,5S,6S)-10-(3,5-dichlorophenylsulfonyl)-2-oxo-3-(pyridin-3-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl...

Basic Information

ID: ALA4835128

Type: Binding

Description: Displacement of fluorescent tracer 5-(3-(4-((1S,5S,6S)-10-(3,5-dichlorophenylsulfonyl)-2-oxo-3-(pyridin-3-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl)-1H-1,2,3-triazol-1-yl)propylcarbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate from recombinant full length C-terminal FLAG-tagged FKBP12.6 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by fluorescence polarisation competition assay

Format: BAO_0000219

Organism: Homo sapiens

Target:  FK506-binding protein 1B(ALA2430)

Document:  ALA4834405

Displacement of fluorescent tracer 5-(3-(4-((1S,5S,6S)-10-(3,5-dichlorophenylsulfonyl)-2-oxo-3-(pyridin-3-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl)-1H-1,2,3-triazol-1-yl)propylcarbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate from recombinant full length C-terminal FLAG-tagged FKBP12.6 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells incubated for 30 mins by fluorescence polarisation competition assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
715.887.847.84
741.928.408.40
787.998.648.64
787.998.648.64
785.988.428.42
771.958.038.03
701.867.457.45
761.916.186.18
757.927.807.80
701.867.457.45
771.958.038.03
773.968.258.25
771.958.038.03
743.948.628.62
729.918.238.23
741.928.408.40
743.897.417.41
741.928.408.40
771.958.038.03
787.957.437.43
741.928.408.40
727.908.018.01
743.948.628.62
761.916.186.18
727.908.018.01
729.918.238.23
773.968.258.25
727.908.018.01
757.927.807.80
703.877.707.70
785.988.428.42
761.916.186.18
743.897.417.41
715.887.847.84