Assay Report Card

Basic Information

ID: ALA4835129

Type: Binding

Description: Selectivity ratio of Kd for displacement of fluorescent tracer 5-(3-(4-((1S,5S,6S)-10-(3,5-dichlorophenylsulfonyl)-2-oxo-3-(pyridin-3-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl)-1H-1,2,3-triazol-1-yl)propylcarbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate from recombinant full length C-terminal FLAG-tagged FKBP12.6 (unknown origin) to Kd for displacement of fluorescent tracer 5-(3-(4-((1S,5S,6S)-10-(3,5-dichlorophenylsulfonyl)-2-oxo-3-(pyridin-3-ylmethyl)-3,10-diazabicyclo[4.3.1]decan-5-yl)-1H-1,2,3-triazol-1-yl)propylcarbamoyl)-2-(6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl)benzoate from recombinant full length C-terminal FLAG-tagged FKBP51 (unknown origin)

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
715.887.847.84
741.928.408.40
787.998.648.64
787.998.648.64
785.988.428.42
771.958.038.03
701.867.457.45
761.916.186.18
757.927.807.80
701.867.457.45
771.958.038.03
773.968.258.25
771.958.038.03
743.948.628.62
729.918.238.23
741.928.408.40
743.897.417.41
741.928.408.40
771.958.038.03
787.957.437.43
741.928.408.40
727.908.018.01
743.948.628.62
761.916.186.18
727.908.018.01
729.918.238.23
773.968.258.25
727.908.018.01
757.927.807.80
703.877.707.70
785.988.428.42
761.916.186.18
743.897.417.41
715.887.847.84