Basic Information
ID: ALA4835172
Type: Binding
Description: Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4835172
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.43 | 1.77 | 1.77 |
| 384.36 | 1.34 | 1.34 |
| 429.30 | 1.24 | 1.24 |
| 426.90 | 2.50 | 2.50 |
| 406.49 | 2.16 | 2.16 |
| 317.35 | -0.28 | -0.28 |
| 342.40 | 0.85 | 0.85 |
| 392.89 | 2.00 | 2.00 |
| 406.49 | 2.16 | 2.16 |
| 316.36 | 0.32 | 0.32 |
| 346.39 | 0.33 | 0.33 |
| 404.90 | 2.07 | 2.07 |
| 439.34 | 2.80 | 2.80 |
| 385.25 | 1.63 | 1.63 |
| 355.44 | 2.16 | 2.16 |
| 406.49 | 2.24 | 2.24 |
| 302.33 | -0.07 | -0.07 |
| 404.90 | 2.15 | 2.15 |
| 413.31 | 2.27 | 2.27 |
| 317.35 | -0.28 | -0.28 |
| 330.39 | 0.71 | 0.71 |
| 330.39 | 0.71 | 0.71 |
| 382.46 | 1.63 | 1.63 |
| 413.31 | 2.41 | 2.41 |
| 344.42 | 1.10 | 1.10 |
| 445.88 | 2.04 | 2.04 |
| 476.36 | 2.94 | 2.94 |
| 370.45 | 1.49 | 1.49 |
| 392.46 | 1.99 | 1.99 |
| 334.35 | 0.46 | 0.46 |
| 425.32 | 2.41 | 2.41 |
| 370.45 | 1.49 | 1.49 |
| 322.41 | 0.45 | 0.45 |
| 404.90 | 2.15 | 2.15 |
| 334.35 | 0.46 | 0.46 |
| 443.33 | 1.89 | 1.89 |
| 420.51 | 2.63 | 2.63 |
| 392.46 | 1.99 | 1.99 |
| 406.49 | 2.16 | 2.16 |
| 385.25 | 1.63 | 1.63 |
| 346.39 | 0.33 | 0.33 |
| 317.35 | -0.28 | -0.28 |
| 344.42 | 1.10 | 1.10 |
| 424.33 | 3.47 | 3.47 |
| 350.81 | 0.98 | 0.98 |
| 427.89 | 1.90 | 1.90 |
| 385.25 | 1.63 | 1.63 |
| 420.46 | 2.02 | 2.02 |
| 462.34 | 2.55 | 2.55 |
| 301.35 | 0.95 | 0.95 |
| 369.47 | 2.34 | 2.34 |
| 459.91 | 2.43 | 2.43 |
| 399.28 | 2.02 | 2.02 |
| 350.81 | 0.98 | 0.98 |
| 390.87 | 1.76 | 1.76 |
| 412.92 | 2.98 | 2.98 |
| 350.81 | 0.98 | 0.98 |
| 441.36 | 2.90 | 2.90 |
| 364.83 | 1.37 | 1.37 |
| 346.39 | 0.33 | 0.33 |