Basic Information
ID: ALA4835178
Type: Binding
Description: Inhibition of human recombinant TACE (AA34 to 660) assessed as cleavage of fluorescent substrate using 5FAM-LAQAVRSSSRK-5TAMRA as substrate by biochemical assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4835178
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 406.43 | 1.77 | 1.77 |
| 429.30 | 1.24 | 1.24 |
| 404.90 | 2.07 | 2.07 |
| 404.90 | 2.15 | 2.15 |
| 413.31 | 2.27 | 2.27 |
| 445.88 | 2.04 | 2.04 |
| 476.36 | 2.94 | 2.94 |
| 443.33 | 1.89 | 1.89 |
| 385.25 | 1.63 | 1.63 |
| 462.34 | 2.55 | 2.55 |
| 459.91 | 2.43 | 2.43 |
| 399.28 | 2.02 | 2.02 |
| 390.87 | 1.76 | 1.76 |
| 441.36 | 2.90 | 2.90 |