Basic Information
ID: ALA4835336
Type: Functional
Description: Ex vivo inhibition of TAFI in Sprague-Dawley rat blood TAFI at 0.6 mg/kg, iv measured after 60 mins by thromboelastometry analysis relative to control
Format: BAO_0000218
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Blood
Target: Carboxypeptidase B2(ALA4879512)
Document: ALA4834413
Ex vivo inhibition of TAFI in Sprague-Dawley rat blood TAFI at 0.6 mg/kg, iv measured after 60 mins by thromboelastometry analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4835336
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.44 | 2.22 | 2.22 |
| 464.47 | 3.54 | 3.54 |
| 447.47 | 2.80 | 2.80 |
| 435.44 | 2.93 | 2.93 |
| 436.42 | 2.32 | 2.32 |
| 452.47 | 2.57 | 2.57 |
| 448.48 | 3.84 | 3.84 |
| 433.45 | 2.08 | 2.08 |
| 432.46 | 3.10 | 3.10 |
| 468.89 | 4.18 | 4.18 |
| 438.44 | 2.26 | 2.26 |
| 434.48 | 2.43 | 2.43 |
| 465.46 | 2.93 | 2.93 |