Basic Information
ID: ALA4835403
Type: Binding
Description: Inhibition of human TRPM2 expressed in HEK293T cells assessed as suppression of H2O2-induced calcium flux at 1 uM measured after 30 mins by Fluo-3/AM assay
Organism: Homo sapiens
Cell type: HEK293T
Activity Charts
Bioactivity
Activity Types for Assay ALA4835403
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.42 | 4.77 | 4.77 |
| 343.38 | 4.70 | 4.70 |
| 267.28 | 3.04 | 3.04 |
| 371.86 | 5.42 | 5.42 |
| 301.73 | 3.69 | 3.69 |
| 281.31 | 3.35 | 3.35 |
| 309.37 | 4.16 | 4.16 |
| 373.41 | 4.71 | 4.71 |
| 325.37 | 4.55 | 4.55 |
| 357.41 | 5.01 | 5.01 |
| 377.83 | 5.36 | 5.36 |
| 311.38 | 4.37 | 4.37 |
| 361.37 | 4.84 | 4.84 |
| 377.83 | 5.36 | 5.36 |
| 352.39 | 2.87 | 2.87 |
| 322.40 | 5.01 | 5.01 |
| 399.49 | 6.00 | 6.00 |
| 377.83 | 5.36 | 5.36 |
| 422.28 | 5.47 | 5.47 |
| 411.38 | 5.72 | 5.72 |
| 350.42 | 4.03 | 4.03 |
| 361.37 | 4.84 | 4.84 |
| 323.39 | 4.33 | 4.33 |
| 416.32 | 5.53 | 5.53 |
| 351.45 | 5.08 | 5.08 |
| 351.45 | 5.08 | 5.08 |
| 373.40 | 5.05 | 5.05 |
| 385.89 | 5.73 | 5.73 |
| 357.41 | 5.01 | 5.01 |
| 337.42 | 4.77 | 4.77 |
| 295.34 | 3.60 | 3.60 |
| 365.47 | 5.39 | 5.39 |
| 311.34 | 3.44 | 3.44 |
| 353.42 | 4.99 | 4.99 |
| 388.38 | 4.61 | 4.61 |
| 411.38 | 5.72 | 5.72 |
| 411.38 | 5.72 | 5.72 |
| 422.28 | 5.47 | 5.47 |
| 326.31 | 3.25 | 3.25 |
| 373.41 | 4.71 | 4.71 |
| 311.38 | 4.37 | 4.37 |
| 391.18 | 3.71 | 3.71 |
| 309.37 | 3.99 | 3.99 |
| 361.37 | 4.84 | 4.84 |
| 371.44 | 5.27 | 5.27 |
| 385.46 | 5.83 | 5.83 |
| 373.41 | 4.71 | 4.71 |
| 367.45 | 5.38 | 5.38 |
| 344.37 | 4.10 | 4.10 |
| 294.39 | 5.29 | 5.29 |
| 357.41 | 5.01 | 5.01 |
| 351.45 | 5.08 | 5.08 |
| 361.37 | 4.84 | 4.84 |
| 361.49 | 5.44 | 5.44 |
| 371.86 | 5.42 | 5.42 |
| 337.42 | 4.77 | 4.77 |
| 357.41 | 5.01 | 5.01 |
| 357.41 | 5.01 | 5.01 |
| 352.39 | 3.17 | 3.17 |
| 347.46 | 5.05 | 5.05 |