Basic Information
ID: ALA4835450
Type: Binding
Description: Inhibition of N-terminal His6-tagged recombinant full length human p110delta/untagged recombinant full length human p85alpha expressed in baculovirus infected Sf21 insect cells using PIP2 as substrate preincubated for 15 mins followed by substrate addition and measured after 1 hr by HTRF assay
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4835450
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 382.47 | 1.98 | 1.98 |
| 436.52 | 2.05 | 2.05 |
| 422.54 | 2.85 | 2.85 |
| 445.45 | 3.35 | 3.35 |
| 365.44 | 2.16 | 2.16 |
| 476.46 | 2.94 | 2.94 |
| 366.43 | 1.55 | 1.55 |
| 437.50 | 2.02 | 2.02 |
| 396.50 | 2.46 | 2.46 |
| 410.53 | 2.85 | 2.85 |
| 413.55 | 3.21 | 3.21 |
| 432.48 | 2.71 | 2.71 |
| 392.47 | 2.03 | 2.03 |
| 436.52 | 2.05 | 2.05 |
| 473.42 | 3.21 | 3.21 |
| 442.47 | 2.67 | 2.67 |
| 490.49 | 3.33 | 3.33 |
| 443.46 | 2.64 | 2.64 |
| 399.43 | 2.00 | 2.00 |
| 368.45 | 1.97 | 1.97 |
| 423.48 | 1.63 | 1.63 |
| 381.44 | 2.00 | 2.00 |
| 394.48 | 2.42 | 2.42 |
| 422.49 | 1.66 | 1.66 |
| 450.47 | 3.00 | 3.00 |
| 419.41 | 2.87 | 2.87 |
| 380.46 | 2.03 | 2.03 |
| 393.45 | 2.00 | 2.00 |
| 491.47 | 2.83 | 2.83 |
| 395.47 | 2.17 | 2.17 |
| 438.49 | 1.52 | 1.52 |
| 419.45 | 1.93 | 1.93 |
| 437.50 | 2.02 | 2.02 |
| 408.51 | 2.78 | 2.78 |
| 381.44 | 1.86 | 1.86 |
| 420.43 | 1.89 | 1.89 |
| 407.48 | 2.39 | 2.39 |
| 446.43 | 3.32 | 3.32 |
| 381.48 | 2.58 | 2.58 |
| 437.51 | 1.55 | 1.55 |
| 406.49 | 2.42 | 2.42 |