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Assay Report Card

Basic Information

ID: ALA4835452

Type: Binding

Description: Inhibition of PI3Kdelta in human Ramos cells assessed as reduction in anti-IgM-antibody-induced phosphorylation of AKT at Ser473 residue preincubated for 20 mins followed by anti-IgM antibody stimulation and measured after 30 mins by alphascreen assay

Organism: Homo sapiens

Cell type: Ramos

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
382.471.981.98
436.522.052.05
422.542.852.85
445.453.353.35
365.442.162.16
476.462.942.94
366.431.551.55
437.502.022.02
396.502.462.46
410.532.852.85
413.553.213.21
432.482.712.71
392.472.032.03
436.522.052.05
473.423.213.21
442.472.672.67
490.493.333.33
443.462.642.64
399.432.002.00
368.451.971.97
394.482.422.42
450.473.003.00
419.412.872.87
380.462.032.03
393.452.002.00
491.472.832.83
395.472.172.17
438.491.521.52
419.451.931.93
437.502.022.02
408.512.782.78
381.441.861.86
420.431.891.89
407.482.392.39
446.433.323.32
381.482.582.58
437.511.551.55
406.492.422.42