Basic Information
ID: ALA4835454
Type: Binding
Description: Inhibition of PI3Kdelta in human whole blood assessed as reduction in anti-CD79b antibody-induced CD69 expression preincubated for 60 mins followed by anti-CD79b antibody stimulation and measured after 3 hrs by FACS analysis
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4835454
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 476.46 | 2.94 | 2.94 |
| 392.47 | 2.03 | 2.03 |
| 436.52 | 2.05 | 2.05 |
| 473.42 | 3.21 | 3.21 |
| 490.49 | 3.33 | 3.33 |
| 443.46 | 2.64 | 2.64 |
| 393.45 | 2.00 | 2.00 |
| 491.47 | 2.83 | 2.83 |
| 437.50 | 2.02 | 2.02 |
| 420.43 | 1.89 | 1.89 |
| 437.51 | 1.55 | 1.55 |
| 406.49 | 2.42 | 2.42 |