Basic Information
ID: ALA4835540
Type: Binding
Description: Inhibition of recombinant human MAT2A expressed in baculovirus infected Sf9 cells assessed as S-adenosyl methionine production using L-methionine as substrate incubated for 60 mins followed by substrate addition and measured after 60 mins
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4835540
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.53 | 5.20 | 5.20 |
| 460.50 | 5.20 | 5.20 |
| 499.58 | 6.33 | 6.33 |
| 384.48 | 4.66 | 4.66 |
| 385.47 | 4.05 | 4.05 |
| 490.57 | 5.86 | 5.86 |
| 391.50 | 4.11 | 4.11 |
| 315.38 | 3.92 | 3.92 |
| 374.45 | 3.38 | 3.38 |
| 442.52 | 5.89 | 5.89 |
| 424.51 | 4.53 | 4.53 |
| 418.50 | 5.78 | 5.78 |
| 428.50 | 5.88 | 5.88 |
| 569.58 | 5.88 | 5.88 |
| 478.56 | 5.79 | 5.79 |
| 474.52 | 5.50 | 5.50 |
| 400.48 | 4.36 | 4.36 |
| 434.54 | 6.26 | 6.26 |
| 485.55 | 6.17 | 6.17 |
| 489.58 | 6.46 | 6.46 |
| 495.55 | 6.04 | 6.04 |
| 439.52 | 4.11 | 4.11 |
| 546.59 | 5.98 | 5.98 |
| 479.54 | 6.05 | 6.05 |
| 393.45 | 5.04 | 5.04 |
| 432.53 | 6.17 | 6.17 |
| 319.34 | 3.80 | 3.80 |
| 414.51 | 4.37 | 4.37 |
| 378.44 | 5.10 | 5.10 |
| 308.37 | 3.12 | 3.12 |
| 301.35 | 3.67 | 3.67 |
| 302.34 | 3.06 | 3.06 |
| 291.31 | 2.39 | 2.39 |
| 305.38 | 3.96 | 3.96 |
| 291.31 | 3.26 | 3.26 |
| 291.31 | 3.26 | 3.26 |
| 293.37 | 3.66 | 3.66 |
| 428.49 | 4.38 | 4.38 |
| 344.37 | 3.32 | 3.32 |
| 317.35 | 3.37 | 3.37 |
| 368.40 | 3.82 | 3.82 |
| 307.40 | 4.05 | 4.05 |
| 302.34 | 2.94 | 2.94 |
| 305.38 | 3.96 | 3.96 |
| 308.39 | 2.99 | 2.99 |
| 291.35 | 3.57 | 3.57 |