Molecular glue activity at CRBN/MDM2 in human CCRF-CEM cells harboring mutant TP53 assessed as induction of MDM2 degradation by western blot analysis

Basic Information

ID: ALA4835711

Type: Binding

Description: Molecular glue activity at CRBN/MDM2 in human CCRF-CEM cells harboring mutant TP53 assessed as induction of MDM2 degradation by western blot analysis

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CCRF-CEM

Target:  Protein cereblon/E3 ubiquitin-protein ligase Mdm2(ALA4523702)

Document:  ALA4834427

Molecular glue activity at CRBN/MDM2 in human CCRF-CEM cells harboring mutant TP53 assessed as induction of MDM2 degradation by western blot analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
846.306.776.77