Basic Information
ID: ALA4835716
Type: Binding
Description: Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation at 100 nM pretreated with CRBN ligand, lenalidomide for 1 hr followed by incubation with compound for 6 hrs by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: RS4-11
Target: Protein cereblon/Epidermal growth factor receptor(ALA4523680)
Document: ALA4834427
Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation at 100 nM pretreated with CRBN ligand, lenalidomide for 1 hr followed by incubation with compound for 6 hrs by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4835716
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 846.30 | 6.77 | 6.77 |