Basic Information
ID: ALA4835721
Type: Binding
Description: Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation at 10 to 100 nM measured after 6 hrs by western blot analysis
Organism: Homo sapiens
Cell type: RS4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA4835721
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 789.21 | 4.79 | 4.79 |
| 826.78 | 7.01 | 7.01 |
| 792.33 | 6.36 | 6.36 |
| 846.30 | 6.77 | 6.77 |