Basic Information
ID: ALA4835732
Type: Binding
Description: Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation at 1 uM incubated for 6 hrs by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: RS4-11
Target: Cereblon/Tumour suppressor p53/oncoprotein Mdm2(ALA4879538)
Document: ALA4834427
Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation at 1 uM incubated for 6 hrs by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4835732
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 951.40 | 7.64 | 7.64 |
| 789.21 | 4.79 | 4.79 |
| 937.37 | 7.25 | 7.25 |
| 866.29 | 6.87 | 6.87 |
| 910.35 | 7.30 | 7.30 |
| 866.29 | 6.87 | 6.87 |
| 896.32 | 6.91 | 6.91 |
| 965.43 | 8.03 | 8.03 |