Basic Information
ID: ALA4835734
Type: Binding
Description: Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation at 100 nM pretreated with MDM2 inhibitor, Ugi ligand 1 for 1 hr followed by incubation with compound for 6 hrs by western blot analysis
Organism: Homo sapiens
Cell type: RS4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA4835734
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 846.30 | 6.77 | 6.77 |