Basic Information
ID: ALA4835757
Type: Binding
Description: Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation by measuring MDM2 level at 10 nM incubated for 6 hrs by western blot analysis (Rvb = 100%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: RS4-11
Target: Protein cereblon/E3 ubiquitin-protein ligase Mdm2(ALA4523702)
Document: ALA4834427
Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation by measuring MDM2 level at 10 nM incubated for 6 hrs by western blot analysis (Rvb = 100%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4835757
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 440.89 | 2.73 | 2.73 |
| 730.26 | 5.18 | 5.18 |
| 846.30 | 6.77 | 6.77 |