Basic Information
ID: ALA4835758
Type: Binding
Description: Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation by measuring MDM2 level at 100 nM incubated for 6 hrs by western blot analysis (Rvb = 100%)
Organism: Homo sapiens
Cell type: RS4-11
Activity Charts
Bioactivity
Activity Types for Assay ALA4835758
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 730.26 | 5.18 | 5.18 |
| 846.30 | 6.77 | 6.77 |