Basic Information
ID: ALA4835760
Type: Binding
Description: Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation by measuring MDM2 level at 1 uM incubated for 6 hrs by western blot analysis (Rvb = 100%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: RS4-11
Target: Protein cereblon/E3 ubiquitin-protein ligase Mdm2(ALA4523702)
Document: ALA4834427
Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation by measuring MDM2 level at 1 uM incubated for 6 hrs by western blot analysis (Rvb = 100%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4835760
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 747.17 | 6.32 | 6.32 |
| 619.16 | 4.52 | 4.52 |
| 706.81 | 5.67 | 5.67 |
| 636.07 | 5.66 | 5.66 |
| 735.20 | 6.12 | 6.12 |
| 666.74 | 4.74 | 4.74 |