Assay Report Card

Basic Information

ID: ALA4835762

Type: Binding

Description: Molecular glue activity at CRBN/MDM2/p53 in human RS4-11 cells assessed as induction of p53 degradation by measuring p53 level at 100 nM incubated for 6 hrs by western blot analysis (Rvb = 100%)

Organism: Homo sapiens

Cell type: RS4-11

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
730.265.185.18
846.306.776.77