Basic Information
ID: ALA4835766
Type: Binding
Description: Molecular glue activity at CRBN/GSPT1 in human RS4-11 cells assessed as induction of GSPT1 degradation by measuring GSPT1 level at 100 nM measured after 6 hrs by western blot analysis (Rvb = 100%)
Format: BAO_0000219
Organism: Homo sapiens
Cell type: RS4-11
Target: Cereblon/GSPT1(ALA4296168)
Document: ALA4834427
Molecular glue activity at CRBN/GSPT1 in human RS4-11 cells assessed as induction of GSPT1 degradation by measuring GSPT1 level at 100 nM measured after 6 hrs by western blot analysis (Rvb = 100%): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4835766
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 730.26 | 5.18 | 5.18 |
| 846.30 | 6.77 | 6.77 |