Basic Information
ID: ALA4835770
Type: Binding
Description: Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation by western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: RS4-11
Target: Protein cereblon/E3 ubiquitin-protein ligase Mdm2(ALA4523702)
Document: ALA4834427
Molecular glue activity at CRBN/MDM2 in human RS4-11 cells assessed as induction of MDM2 degradation by western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4835770
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 826.78 | 7.01 | 7.01 |
| 798.72 | 6.23 | 6.23 |
| 778.31 | 5.97 | 5.97 |
| 860.33 | 7.16 | 7.16 |
| 818.25 | 5.99 | 5.99 |
| 764.28 | 5.58 | 5.58 |
| 874.36 | 7.55 | 7.55 |
| 792.33 | 6.36 | 6.36 |
| 888.38 | 7.94 | 7.94 |
| 812.75 | 6.62 | 6.62 |
| 846.30 | 6.77 | 6.77 |
| 902.41 | 8.33 | 8.33 |
| 832.28 | 6.38 | 6.38 |