Basic Information
ID: ALA4835773
Type: Binding
Description: Inhibition of His6-tagged SIRT1 (unknown origin) expressed in Escherichia coli BL21 (DE3) preincubated for 15 mins followed by NAD+ addition and measured after 30 mins by FLucK529Ac based luminescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4835773
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.71 | 2.73 | 2.73 |
| 178.19 | 0.34 | 0.34 |
| 256.28 | -0.30 | -0.30 |
| 192.22 | 0.37 | 0.37 |
| 336.31 | 2.96 | 2.96 |
| 293.33 | 1.81 | 1.81 |
| 282.34 | 2.25 | 2.25 |
| 325.37 | 1.90 | 1.90 |
| 394.21 | 2.54 | 2.54 |
| 312.33 | 1.59 | 1.59 |
| 330.77 | 2.32 | 2.32 |
| 220.23 | 0.29 | 0.29 |
| 326.35 | 1.73 | 1.73 |
| 269.30 | 2.54 | 2.54 |
| 325.37 | 1.90 | 1.90 |
| 312.32 | 1.64 | 1.64 |
| 297.35 | 3.02 | 3.02 |
| 349.39 | 1.58 | 1.58 |
| 293.33 | 1.81 | 1.81 |
| 283.33 | 1.52 | 1.52 |
| 282.34 | 2.20 | 2.20 |
| 313.31 | 1.85 | 1.85 |
| 325.37 | 1.90 | 1.90 |
| 268.32 | 1.94 | 1.94 |
| 344.41 | 3.61 | 3.61 |
| 332.38 | 1.44 | 1.44 |
| 292.33 | 1.08 | 1.08 |
| 283.29 | 0.97 | 0.97 |
| 298.34 | 1.95 | 1.95 |
| 310.31 | 1.48 | 1.48 |
| 282.30 | 1.58 | 1.58 |
| 312.33 | 1.67 | 1.67 |
| 286.31 | 2.08 | 2.08 |
| 269.30 | 1.33 | 1.33 |
| 368.43 | 2.89 | 2.89 |
| 302.76 | 2.59 | 2.59 |
| 368.41 | 2.28 | 2.28 |
| 313.31 | 1.85 | 1.85 |
| 290.35 | 0.98 | 0.98 |
| 207.23 | 1.42 | 1.42 |
| 404.31 | 3.98 | 3.98 |
| 179.17 | 0.94 | 0.94 |
| 332.39 | 1.35 | 1.35 |
| 296.37 | 2.56 | 2.56 |
| 349.39 | 1.58 | 1.58 |
| 326.35 | 1.73 | 1.73 |
| 336.44 | 3.47 | 3.47 |
| 296.37 | 2.54 | 2.54 |
| 216.24 | 0.37 | 0.37 |
| 336.31 | 2.96 | 2.96 |
| 347.21 | 2.70 | 2.70 |
| 298.34 | 1.95 | 1.95 |
| 327.34 | 1.98 | 1.98 |
| 322.32 | 1.84 | 1.84 |
| 262.31 | 1.31 | 1.31 |
| 313.31 | 1.85 | 1.85 |
| 347.21 | 2.70 | 2.70 |
| 284.31 | 1.65 | 1.65 |
| 390.47 | 2.74 | 2.74 |
| 311.34 | 2.28 | 2.28 |
| 269.30 | 1.33 | 1.33 |