Basic Information
ID: ALA4835865
Type: Functional
Description: Antiviral activity against HBV infected in human HepG2-NTCP cells assessed as reduction in HBeAg secretion incubated for 24 hrs followed replacement with fresh medium and measured at day 5 post infection by ELISA
Organism: Hepatitis B virus
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA4835865
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 997.41 | 6.55 | 6.55 |
| 905.31 | 9.32 | 9.32 |
| 874.28 | 8.36 | 8.36 |
| 1065.49 | ||
| 1093.54 | ||
| 1367.70 | ||
| 1073.51 | ||
| 900.35 | 9.82 | 9.82 |
| 1063.51 | ||
| 916.30 | 8.50 | 8.50 |
| 914.37 | 10.21 | 10.21 |
| 888.31 | 8.75 | 8.75 |
| 872.29 | 9.04 | 9.04 |
| 752.18 | 8.92 | 8.92 |
| 918.36 | 7.23 | 7.23 |
| 903.35 | 8.46 | 8.46 |
| 1023.50 | ||
| 897.32 | 8.43 | 8.43 |
| 986.41 | 8.31 | 8.31 |
| 1065.58 | ||
| 1095.51 | ||
| 1095.51 | ||
| 790.19 | 9.51 | 9.51 |
| 753.16 | 9.34 | 9.34 |
| 1023.44 | ||
| 847.28 | 9.78 | 9.78 |
| 1062.49 | ||
| 1123.57 | ||
| 886.32 | 9.43 | 9.43 |
| 928.40 | 10.60 | 10.60 |
| 879.28 | 9.39 | 9.39 |
| 963.40 | 8.38 | 8.38 |
| 917.37 | 8.85 | 8.85 |
| 979.44 | 10.16 | 10.16 |
| 1248.84 | ||
| 1093.54 | ||
| 873.29 | 7.93 | 7.93 |
| 905.32 | 7.31 | 7.31 |
| 832.29 | 8.60 | 8.60 |
| 965.41 | 8.32 | 8.32 |
| 960.41 | 10.11 | 10.11 |