Basic Information
ID: ALA4835968
Type: Binding
Description: Positive allosteric modulation of C57BL/6 mouse NMDA receptor assessed as fold change in compound potentiated NMDA-induced current relative to NMDA current alone at 30 uM measured after 15 to 30 mins by patch-clamp method
Organism: Mus musculus
Strain: C57BL/6
Tissue: Brain
Activity Charts
Bioactivity
Activity Types for Assay ALA4835968
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.27 | 4.46 | 4.46 |
| 280.12 | 3.60 | 3.60 |
| 364.23 | 4.70 | 4.70 |
| 404.33 | 4.93 | 4.93 |
| 472.17 | 6.12 | 6.12 |
| 324.38 | 3.44 | 3.44 |
| 362.46 | 4.41 | 4.41 |
| 339.40 | 2.93 | 2.93 |
| 363.85 | 4.65 | 4.65 |
| 444.92 | 3.55 | 3.55 |
| 408.68 | 4.81 | 4.81 |
| 388.50 | 4.92 | 4.92 |
| 448.91 | 5.30 | 5.30 |
| 387.82 | 3.83 | 3.83 |
| 347.39 | 4.14 | 4.14 |
| 327.36 | 3.84 | 3.84 |
| 462.94 | 4.98 | 4.98 |
| 402.29 | 4.72 | 4.72 |
| 380.30 | 5.17 | 5.17 |
| 432.27 | 3.94 | 3.94 |
| 314.57 | 4.26 | 4.26 |
| 361.47 | 5.02 | 5.02 |
| 343.43 | 4.31 | 4.31 |
| 435.30 | 5.26 | 5.26 |
| 496.20 | 5.89 | 5.89 |
| 472.17 | 6.12 | 6.12 |
| 397.78 | 5.07 | 5.07 |
| 442.24 | 5.17 | 5.17 |
| 347.78 | 4.19 | 4.19 |
| 451.75 | 5.78 | 5.78 |
| 479.31 | 4.74 | 4.74 |
| 350.45 | 4.34 | 4.34 |
| 399.52 | 4.66 | 4.66 |
| 363.85 | 4.65 | 4.65 |
| 343.43 | 4.31 | 4.31 |
| 359.88 | 4.82 | 4.82 |
| 359.81 | 3.54 | 3.54 |
| 345.40 | 4.55 | 4.55 |
| 463.33 | 4.83 | 4.83 |
| 387.51 | 5.53 | 5.53 |
| 371.46 | 3.88 | 3.88 |
| 402.52 | 5.23 | 5.23 |
| 371.37 | 3.32 | 3.32 |
| 435.30 | 5.26 | 5.26 |
| 296.33 | 2.79 | 2.79 |
| 309.37 | 3.70 | 3.70 |
| 367.43 | 3.03 | 3.03 |
| 428.92 | 4.58 | 4.58 |
| 336.78 | 2.69 | 2.69 |
| 472.17 | 6.12 | 6.12 |
| 371.44 | 5.06 | 5.06 |
| 362.46 | 4.41 | 4.41 |
| 371.44 | 5.06 | 5.06 |
| 380.30 | 5.17 | 5.17 |
| 430.89 | 3.16 | 3.16 |
| 401.54 | 5.84 | 5.84 |
| 295.34 | 3.39 | 3.39 |
| 374.24 | 4.16 | 4.16 |
| 351.44 | 3.74 | 3.74 |
| 343.81 | 4.36 | 4.36 |
| 294.15 | 3.91 | 3.91 |