Selectivity index, ratio of pIC50 for binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD1 domain (unknown origin) to pIC50 for binding affinity ...

Basic Information

ID: ALA4836636

Type: Binding

Description: Selectivity index, ratio of pIC50 for binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD1 domain (unknown origin) to pIC50 for binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin)

Format: BAO_0000019

Organism: Homo sapiens

Target: Unchecked(ALA612545)

Document: ALA4834466

Selectivity index, ratio of pIC50 for binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD1 domain (unknown origin) to pIC50 for binding affinity to 6His-Thr-BRD4 (1 to 477 residues) BD2 domain Y390A mutant (unknown origin): 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4836636

Ratio pIC50

Total(40)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
342.37	2.27	2.27
471.53	2.12	2.12
325.37	1.15	1.15
410.45	2.28	2.28
368.41	2.80	2.80
328.34	2.01	2.01
364.45	2.88	2.88
396.42	2.08	2.08
324.38	2.10	2.10
366.42	2.47	2.47
392.46	2.12	2.12
380.44	1.86	1.86
336.39	2.46	2.46
406.48	2.24	2.24
408.50	2.78	2.78
386.45	1.32	1.32
392.46	2.07	2.07
376.42	2.56	2.56
379.42	1.34	1.34
310.35	1.93	1.93
439.51	1.78	1.78
404.47	2.28	2.28
379.42	1.34	1.34
392.46	2.25	2.25
354.38	2.60	2.60
296.33	1.67	1.67
443.51	2.76	2.76
382.44	3.05	3.05
378.43	1.95	1.95
433.51	2.17	2.17
379.42	1.34	1.34
406.48	2.24	2.24
375.43	2.94	2.94
354.38	2.60	2.60
408.45	1.95	1.95
350.42	2.64	2.64
417.47	2.43	2.43
408.45	1.09	1.09
350.42	2.71	2.71
406.48	2.51	2.51