Basic Information
ID: ALA4836673
Type: Binding
Description: Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In-cell Western analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: A-431
Target: Cyclin-dependent kinase 9(ALA3116)
Document: ALA4834469
Inhibition of CDK9 in human A-431 cells assessed as reduction in RNA polymerase2 phosphorylation at C-terminal ser2 residue incubated for 4 hrs by In-cell Western analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4836673
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 323.37 | 3.75 | 3.75 |
| 381.41 | 2.99 | 2.99 |
| 401.46 | 3.43 | 3.43 |
| 380.42 | 3.81 | 3.81 |
| 366.39 | 4.65 | 4.65 |
| 381.41 | 3.55 | 3.55 |
| 437.52 | 5.01 | 5.01 |
| 463.55 | 5.50 | 5.50 |
| 463.55 | 5.50 | 5.50 |
| 467.52 | 5.25 | 5.25 |
| 481.54 | 5.64 | 5.64 |
| 464.54 | 4.02 | 4.02 |
| 474.51 | 3.46 | 3.46 |
| 467.52 | 5.25 | 5.25 |
| 481.54 | 5.64 | 5.64 |
| 443.50 | 3.64 | 3.64 |
| 449.53 | 5.11 | 5.11 |
| 449.53 | 5.11 | 5.11 |
| 463.55 | 5.50 | 5.50 |
| 464.54 | 4.02 | 4.02 |
| 395.43 | 3.99 | 3.99 |
| 463.55 | 5.36 | 5.36 |
| 449.53 | 5.11 | 5.11 |