Basic Information
ID: ALA4836725
Type: Binding
Description: Inhibition of 5-LOX in LPS-stimulated human monocytes assessed as reduction in 5-LOX product formation prestimulated with LPS for 24 hrs followed by compound addition for 15 mins followed by AA and A23187 addition by UPLC-MS.MS analysis
Organism: Homo sapiens
Cell type: PMNL
Activity Charts
Bioactivity
Activity Types for Assay ALA4836725
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 460.70 | 7.90 | 7.90 |
| 456.67 | 6.55 | 6.55 |